Performance Report - Biotech

EH Quantitative Directional Long

The strategy actively trades a curated universe of over 200 investible tickers with material or enabling exposure to biotechnology, taking positions based on a proprietary technical ranking derived from a multi-factor analysis of market action across multiple trading horizons.

Forward test from inception 2023/01/03 to 2026/09/15

Overview

Annualized Returns: 115.87% Average Win Size: 3,548.21
Maximum Drawdown: 16.52% Average Loss Size: 2,281.84
Return over Maximum Drawdown: 7.01 Win/Loss Size Ratio: 1.55
Sharpe Ratio (Annualized): 2.51 Number of Closed and Open Positions: 2394
Sortino Ratio (Annualized): 0.46 Average Trade Value: 35,740 USD
Number of Wins: 1256 Average Closed Trade Duration: 7.0 days
Number of Losses: 1138 Last Session Move: 35,955.00 (1.86%), Baseline move: (-0.44%)
Win/Loss Count Ratio: 1.10 (52% winners) Win Months(%) 86.7%
Includes 6 open positions with cash holdings of 1,513,653.82 USD

Cash holdings are equivalent to 77% of Total Strategy Value (1,966,224.82 USD) at this time.

Monthly Strategy Returns (%):

  Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Total
2023 31.7 -0.1 22.2 24.1 25.5 9.2 12.8 -6.3 4.5 0.1 14.7 15.2 153.6
2024 17 15.5 4.5 -2.1 3.2 1.5 5.5 3.5 0.7 4 6.6 1.2 61.1
2025 1.7 2.5 0.4 3.2 0.6 6.4 4 4.5 8.8 0.6 2.8 -0.1 35.4
2026 1.5 7 1.4 9.5 14.5 11 -2.7 7.9 -0.7 0 0 0 49.4

Open Positions:

Symbol Name Entry Date # Shares Entry Price Present Price Move Max Move Days HeldPrice Trailing Stop Profit Annualized
NTRANatera2026-08-28100335.28350.784.62%4.62%12 337.268 (3.9%)1,550.0092.4%
BLFSBioLife Solutions, Inc.2026-09-01210036.9836.39-1.59%0.24%10 34.951 (4%)-1,239.00-38.2%
TTRXTurn Therapeutics Inc.2026-09-09480013.3013.461.20%1.20%5 12.263 (8.9%)768.0057.7%
ABUSArbutus Biopharma2026-09-09125005.175.06-2.12%0.19%5 5.020 (0.8%)-1,375.00-102.1%
SIONSionna Therapeutics, Inc.2026-09-15123007.876.88-12.57%4.95%1 5.354 (22.2%)-12,177.00-3,019.0%
BNGOBionano Genomics, Inc.2026-09-15744001.311.5619.08%19.08%1 1.373 (12%)18,600.004,580.1%
Total Value (USD) of 6 Open Positions:440,043.006,127.0061.7%

Closed Month-To-Date Performance:

Symbol Name # Shares Buy Date Buy Price Sell Date Sell Price Max Move DurationPrice Profit ROI
ILMNIllumina3002026-08-26220.782026-09-01209.753.12%5 -3,309.00-5%
ARCTArcturus Therapeutics51002026-08-2715.742026-09-0116.233.11%4 2,499.003.1%
RAPPRapport Therapeutics, Inc.15002026-08-2650.952026-09-0248.693.04%6 -3,390.00-4.4%
VIRViriBio73002026-08-2711.002026-09-0311.505.72%6 3,650.004.5%
QNCXQuince Therapeutics, Inc.28002026-08-3134.042026-09-0331.760.00%4 -6,384.00-6.7%
CAPRCapricor Therapeutics, Inc.75002026-09-0110.772026-09-039.690.00%3 -8,100.00-10%
INMBINmune Bio328002026-08-272.472026-09-042.440.00%7 -984.00-1.2%
DWTXDogwood Therapeutics, Inc.373002026-08-312.612026-09-042.353.44%5 -9,698.00-10%
SRPTSarepta Therapeutics38002026-09-0221.332026-09-0422.548.81%3 4,598.005.7%
AMGNAmgen Inc.1002026-08-24440.312026-09-08401.041.21%11 -3,927.00-8.9%
HALOHalozyme Therapeutics7002026-08-25109.332026-09-08108.661.30%10 -469.00-0.6%
BIIBBiogen Inc.2002026-08-28221.172026-09-08215.451.93%7 -1,144.00-2.6%
ADILAdial Pharmaceuticals131002026-08-246.192026-09-115.5715.02%14 -8,122.00-10%
JANXJanux Therapeutics, Inc.43002026-08-2518.722026-09-1117.928.11%13 -3,440.00-4.3%
RVMDRevolution Medicines2002026-08-28220.722026-09-11204.380.19%10 -3,268.00-7.4%
EOLSEvolus110002026-08-318.852026-09-117.975.08%9 -9,680.00-9.9%
RCKTRocket Pharmaceuticals258002026-08-313.772026-09-113.443.44%9 -8,514.00-8.8%
ZYMEZymeworks27002026-09-0129.322026-09-1126.436.88%8 -7,803.00-9.9%
CRDLCardiol Therapeutics Inc.376002026-09-022.162026-09-112.032.77%7 -4,888.00-6%
SDGRSchrodinger, Inc.39002026-09-0220.672026-09-1119.021.74%7 -6,435.00-8%
TARSTarsus Pharmaceuticals7002026-09-0382.762026-09-1182.279.69%6 -343.00-0.6%
CABACabaletta Bio179002026-09-033.632026-09-113.270.00%6 -6,444.00-9.9%
LENZLENZ Therapeutics, Inc.110002026-09-035.902026-09-115.311.01%6 -6,490.00-10%
RPRXRoyalty Pharma plc10002026-09-0463.552026-09-1158.950.64%5 -4,600.00-7.2%
VRTXVertex Pharmaceuticals Incorporated1002026-09-04549.502026-09-11518.771.72%5 -3,073.00-5.6%
GALTGalectin Therapeutics Inc.141002026-09-084.602026-09-114.140.21%4 -6,486.00-10%
HOWLWerewolf Therapeutics, Inc.820002026-08-270.992026-09-140.9650.80%12 -2,050.00-2.5%
IOVAIovance Biotherapeutics75002026-09-038.652026-09-149.267.05%7 4,575.007.1%
SMMTSummit Therapeutics37002026-09-0817.432026-09-1418.425.67%5 3,663.005.7%
CORCencora, Inc.1002026-09-04333.482026-09-15324.141.32%7 -934.00-2.8%
TXG10X Genomics9002026-09-0967.402026-09-1574.3910.37%5 6,291.0010.4%
INDPIndaptus Therapeutics, Inc.348002026-09-142.802026-09-153.6430.00%2 29,232.0030%

Month-To-Date Summary:
MTD Win Trades %:21.8%
MTD Avg # Entry Trades per Day:1.6
MTD Avg # Positions Held:16.2
MTD Win/Loss Size Ratio:1.62
MTD Avg Trade Duration:6.8
MTD Strategy Performance:-0.83%
MTD Baseline (^GSPC) Performance:-1.30%
MTD Strategy Outperformance compared to Baseline:0.47%
Sold Today:COR, TXG, INDP
Pending Buys:TMO, ILMN

Notes:

The performance data quoted represents past performance. Past performance does not guarantee future results. The investment return and principal value of an investment will fluctuate so that an investor's position, when redeemed, may be worth more or less than the original cost. Current performance may be lower or higher than the performance data quoted. Investors should consider the investment objectives, risks, and charges and expenses of the above system carefully before investing.

Last Session Date: 2026/09/15